High shear mixer with integrated wet granulator TCT-3/5 | Integrated Mixing & Granulation | T&T MACHINERY

T&T MACHINERY | GMP-STANDARD
0903.845.108 - 0909.877.646 - 039.88888.39

High shear mixer with integrated wet granulator TCT-3/5

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  • High shear mixer with integrated wet granulator TCT-3/5 is a modern system designed for powder mixing and wet granulation in formulation research and development (R&D) and small-scale production. With a batch capacity of 3–5 kg, the machine ensures fast, uniform mixing and in-line granulation within a single system, helping save space, shorten operation time, and reduce material loss. The equipment is manufactured from SUS 316L and 304 stainless steel, fully compliant with international GMP standards.


    ⚙️ General Construction of the High shear mixer with integrated wet granulator TCT-3/5

    • Machine body & mixing bowl

    • Main impeller & high-speed chopper

    • In-line wet granulator: integrated on the same system for post-mixing material processing

    • Control system: PLC + touch-screen HMI


    🔄 Working Principle

    1. Material charging
    Powder is loaded into the mixing bowl; binder solution is added through the dosing hopper.

    2. Mixing process

    • The main impeller rotates at low to medium speed to uniformly blend the entire powder mass.

    • The high-speed chopper disperses the binder and cuts through the material, allowing uniform wet mass formation.

    3. In-line granulation
    Once the desired endpoint is achieved, the wet mass is discharged directly through the integrated granulator. The granulation screen determines particle size, producing wet granules with high uniformity.

    4. Product collection
    The wet granules are collected and transferred to the fluid-bed dryer or tray dryer for the drying step.

  • Product information

    High shear mixer with integrated wet granulator TCT-3/5– T&T MACHINERY

    The High shear mixer with integrated wet granulator TCT-3/5 is designed and manufactured by T&T MACHINERY using SUS 316L stainless steel for all product-contact parts, fully compliant with GMP-WHO & ISO standards. The system integrates mixing and wet granulation in a single machine, making the R&D process for pharmaceuticals, cosmetics, and food applications faster, more efficient, and minimizing material loss. The machine is easy to operate with a PLC and touch-screen HMI interface.

    Video: High shear mixer with integrated wet granulator TCT-3/5 installed at Dong Thap Medical College

    Key Advantages of the High shear mixer with integrated wet granulator TCT-3/5

    Two processes integrated into one machine

    After mixing, the wet mass is discharged directly through the in-line granulator without transferring to another equipment.
    This shortens the process flow, reduces the number of machines required, saves cleanroom space, and optimizes investment costs.

    T&T MACHINERY High shear mixer with integrated wet granulator TCT-3/5
    T&T MACHINERY High shear mixer with integrated wet granulator TCT-3/5

    Uniform and stable granule quality

    The combination of a low–medium speed main impeller and a high-speed chopper ensures strong dispersion, allowing the binder to be distributed evenly.
    The in-line granulation process controls particle size, resulting in smooth, uniform wet granules.


    Material savings with higher process efficiency

    Ideal for small batches (3–5 kg), reducing loss of valuable materials during formula development or trial production.
    The design accurately simulates large-scale production conditions, making scale-up easier and more reliable.


    User-friendly, easy operation

    Automatic control via PLC with a 7-inch touch-screen HMI (Vietnamese language supported).
    Operators can easily set parameters and monitor machine status, minimizing operating errors.


    Maximum safety for both product and operator

    Automatic alarms and shutdown protection in case of incidents such as: low air pressure, open lid, overload, phase failure, etc.
    Enclosed design with dust filter and safe viewing window.
    Fully compliant with GMP-WHO & IEC safety regulations.


    Premium materials – high durability

    All product-contact surfaces are made of SUS 316L, ensuring corrosion resistance, easy cleaning, and product safety.
    Other components are constructed from SUS 304 for strength and durability.
    Internal surfaces are rounded (R-edge finish) to prevent material buildup and minimize cross-contamination.


    Complete documentation and technical support

    Full documentation package provided, including: IQ/OQ validation, factory inspection reports, catalog, electrical & pneumatic diagrams.
    Material certificates for SUS 316L are available.
    On-site installation and operation training ensure full technology transfer to the customer.

    See more: Other R&D-scale equipment by T&T MACHINERY

    Key customers using T&T MACHINERY High shear mixer with integrated wet granulator TCT-3/5

    • Stellapharm
    • An Phú Khang Cosmeceuticals 
    • v..v

    Technical specifications of High shear mixer with integrated wet granulator TCT-3/5

    Model

    High shear mixer with integrated wet granulator TCT-3/5

    Mixing volume

    9 L

    Capacity

    Max 3 kg/batch

    Mixing time

    5 – 15 mins/ batch

    Chopper Motor 

    0,75 kW – 1.400–2.900 rpm, controlled by ABB frequency inverter

    Mixing Motor

    1,5 kW – 145–290 rpm, controlled by ABB frequency inverter

    Motor of wet granulator

    0,5 HP, controlled by ABB frequency inverter

    Wet granulation mesh

    3 sets of different sizes

    Control system

    Auto and semi-auto

    Voltage

    380V, 3 pha, 50Hz

    0903.845.108 - 0909.877.646 - 039.88888.39
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