R&D MiniLab Machines – The Smart & Cost-Saving Solution by T&T MACHINERY
Date Submitted:
18/08/2025
Introduction to the R&D MiniLab Series by T&T MACHINERY
In an era of constant innovation, fast – accurate – cost-effective product development is the lifeline of every pharmaceutical, cosmetic, and food enterprise. This is why the R&D MiniLab series from T&T MACHINERY has become the top choice for modern factories, especially Start-up-stage facilities.
🔍What is an R&D machine and why do you need it?
R&D (Research & Development) machines are specialized equipment used for formulating, testing, and refining products before mass production. The MiniLab line from T&T MACHINERY is designed in a compact scale while maintaining the same functionality, precision, and standards as industrial-scale machines.
⚙️A diverse range of equipment — suitable for every R&D stage
T&T MACHINERY provides a complete set of equipment for R&D laboratories, from Pilot scale (a few kilograms) to MiniLab scale (a few hundred grams):
Mixers: for wet mixing, dry mixing, and herbal extract mixing
Dryers: including small-scale fluid-bed granulation, spray drying, and microwave drying
Film coaters: for tablet coating trials
Concentration & extraction systems: for cost-efficient herbal extract concentration
Emulsifying mixers: for small-batch creams, gels, and liquid formulations
Hydrolysis machines: for compound separation
…and many other customizable machines.
T&T MACHINERY R&D MiniLab machines
👉 T&T MACHINERY’s solutions support the entire process — from early-stage research to stability evaluation under simulated production conditions.
The Micro-Scale R&D Granulation System consists of a 100 g High-Shear Mixer integrated with a 100 g Fluid-Bed Dryer Granulator, manufactured by T&T MACHINERY. This system is crucial for pharmaceutical formulation research and process optimization before scaling up to full-scale production lines.
🔧 1. System Structure — Micro-Scale R&D Granulation system TCT-100g & FBDG-100g
1. High-Shear Mixer Granulator – 100 g
Working capacity: approx. 100 g — ideal for formulation development and new product trials.
Main components:
Main impeller: kneads and blends powder materials.
Chopper blade: breaks wet mass into uniform granules.
Applications:
Wet granulation for tablets and capsules.
Improves granule uniformity and mechanical strength.
Advantages:
Easy control of mixing speed and processing time.
Suitable for both pharmaceuticals and nutraceuticals.
2. Fluid-Bed Dryer Granulator – 100 g
Drying capacity: approx. 100 g of wet granules.
Working principle:
Heated air flows upward, fluidizing the granule bed.
Moisture evaporates rapidly, resulting in uniform drying.
Equipped with a top-spray granulation system.
Features:
Adjustable temperature, airflow, and drying time.
Integrated dust collection filter.
Advantages:
Fast drying, uniform granulation.
No degradation of active ingredients.
✅ 2. Integrated System
The two units can be integrated to:
Transfer wet granules directly from the mixer to the fluid bed.
Reduce manual handling and avoid cross-contamination.
Easily evaluate formulation, processing time, and residual moisture.
🎯 3. Applications in R&D Laboratories
Used for:
Development of new pharmaceutical formulations.
Adjustment of excipients, solvents, and granulation parameters.
Process optimization prior to scale-up into large-scale production lines.
Micro-scale R&D Granulation System composed of a 150 g High-Shear Mixer integrated with a 300 g Fluid-Bed Granulator Dryer, manufactured by T&T MACHINERY, is a critical system for pharmaceutical formulation research and process optimization before scaling up to industrial production lines.
🔧 1. System Structure — Micro-Scale R&D Granulation system TCT-150g & FBDG-300g
1. High-Shear Mixer Granulator – 150 g
Working capacity: approx. 150 g — ideal for formulation studies and new product trials.
Main components:
Main impeller: blends and kneads powder materials.
Chopper blade: breaks wet mass into uniform granules.
Applications:
Wet granulation for tablets or capsules.
Enhances granule uniformity and mechanical strength.
Advantages:
Easy control of mixing speed and processing time.
Suitable for both pharmaceutical and nutraceutical formulations.
2. Fluid-Bed Dryer Granulator – 300 g
Drying capacity: approx. 300 g of wet granules.
Working principle:
Heated air flows upward, fluidizing the granule bed.
🧠 Why is the R&D MiniLab considered a “smart and ultra-cost-saving solution”?
💰 Optimize costs – Minimize investment risks
Investing in the R&D MiniLab is a strategic move that helps businesses significantly reduce the cost of formula trials and process evaluation before moving to mass production. Instead of running a full-scale production line to test a new formula, manufacturers can use the MiniLab equipment to:
Run small trial batches (200–500 g) instead of tens of kilograms of raw materials
Avoid wasting expensive ingredients when formulas do not meet requirements
Reduce energy consumption, labor, and setup time
Increase the number of trials per day thanks to compact, easy-to-operate, easy-to-clean equipment
✅ Example: A trial batch using a MiniLab fluid-bed dryer requires only 300–500 g of material, compared to 5–10 kg on an industrial machine. This allows businesses to save up to 90% of testing materials.
R&D MiniLab TCT-100g & FBDG-100g Granulation line T&T MACHINERY
🧪 Save raw materials – Especially valuable for rare herbs and high-cost active ingredients
In the pharmaceutical and cosmetic industries, many ingredients are extremely expensive or require special preservation. Using R&D MiniLab equipment helps minimize the consumption of these materials during research and development:
🔹 Pharmaceutical industry:
High-value active pharmaceutical ingredients (APIs) / oncology (anti-cancer) actives
Rosuvastatin
Herbal extracts of high value, such as: Ginseng extract, Pseudoginseng extract, Polyscias fruticosa (Đinh lăng) extract
🔹 Cosmetic industry:
Rare natural extracts such as: Bulgarian rose essential oil, Spirulina, Saffron stigma
High-value actives such as: Hyaluronic Acid, Niacinamide, Retinol, Peptides
Hyaluronic Acid
🔹 Functional food industry:
Granulated or gel-form multivitamins
Soluble fibers, plant-based proteins, digestive enzymes, etc.
👉 Saving just a few hundred grams of these materials is not only about reducing cost — it also helps the laboratory preserve scarce samples for multiple trials, especially in international collaboration projects or advanced research programs.
🧠Fast switching – Maximum flexibility
After each trial, R&D MiniLab equipment can be cleaned easily, allowing quick formula changes and product switching without stopping the entire production line. This is especially ideal for:
R&D laboratories conducting multiple formulations per day
Companies in the process of developing new products
Businesses producing samples for testing or regulatory approval
🏆 High standards – Compact machines that still meet full GMP requirements
One of the standout advantages of the R&D MiniLab series from T&T MACHINERY is that despite its compact size, it is manufactured according to GMP-WHO, EU-GMP, and Japan-GMP standards — some of the strictest regulations in the pharmaceutical industry. This ensures that test results obtained from MiniLab equipment can be seamlessly scaled up to industrial production without needing to adjust the formula or process.
✅ GMP-compliant materials:
316L stainless steel for all product-contact parts — corrosion-resistant and non-reactive with pharmaceutical or cosmetic chemicals.
304 stainless steel for the machine frame and exterior panels — durable and easy to clean.
Acrylic or heat-resistant glass for viewing chambers — allowing visual monitoring while maintaining airtightness and hygiene.
R&D MiniLab FSC-300g Film coater T&T MACHINERY
✅ Automatic control system – simulating a real production line:
7–10 inch HMI touchscreen, user-friendly and programmable for customized processes.
Japan-made PLC ensures high stability and flexible programming for different formulations.
Direct printing of product parameters from the machine, supporting quality testing and documentation.
Optional SCADA connectivity for data retrieval, ready for integration into the factory’s full quality-control system.
✅ Easy-to-clean design – compliant with “clean in place” principles:
All components are easily removable for cleaning, minimizing cross-contamination risks between formulations.
Certain models can be connected to HEPA filtration systems or cartridge dust collectors, meeting the strict requirements of pharmaceutical manufacturing.
📌 Research results from the R&D MiniLab can be used directly for product quality registration, laboratory testing, or submissions to the Drug Administration / Department of Health — without needing to modify the process for larger equipment.
🏭 Who should invest in R&D MiniLab equipment?
👉 Pharmaceutical, cosmetic, and food manufacturers aiming for continuous product improvement
👉 Universities, research institutes, and testing laboratories
👉 Startups developing health-care or nutraceutical products
👉 Factories targeting export markets with strict testing and regulatory requirements
🌐T&T MACHINERY – Your Trusted Partner in Innovative Research
With more than two decades of experience in manufacturing machinery for the Pharmaceutical – Cosmetic – Food industries, T&T MACHINERY is proud to be the trusted partner of hundreds of factories in Vietnam and abroad. The R&D MiniLab series is the result of a perfect synergy between:
Advanced mechanical and electronic engineering
Deep industry expertise in pharmaceuticals
Highly flexible customization tailored to each laboratory’s requirements
Factory: 174-175 Dang Cong Binh St., Xuan Thoi Son Ward, Ho Chi Minh City, Vietnam
Registered Office: 82 Giai Phong St., Tan Son Nhat Ward, Ho Chi Minh City, Vietnam
+84.903845108 | +84.398888839 | +84.909877646 
tivati7@gmail.com
tivati.com.vn
