The Micro-Scale R&D Granulation System consists of a 100 g High-Shear Mixer integrated with a 100 g Fluid-Bed Dryer Granulator, manufactured by T&T MACHINERY. This system is crucial for pharmaceutical formulation research and process optimization before scaling up to full-scale production lines.
Working capacity: approx. 100 g — ideal for formulation development and new product trials.
Main components:
Main impeller: kneads and blends powder materials.
Chopper blade: breaks wet mass into uniform granules.
Applications:
Wet granulation for tablets and capsules.
Improves granule uniformity and mechanical strength.
Advantages:
Easy control of mixing speed and processing time.
Suitable for both pharmaceuticals and nutraceuticals.
Drying capacity: approx. 100 g of wet granules.
Working principle:
Heated air flows upward, fluidizing the granule bed.
Moisture evaporates rapidly, resulting in uniform drying.
Equipped with a top-spray granulation system.
Features:
Adjustable temperature, airflow, and drying time.
Integrated dust collection filter.
Advantages:
Fast drying, uniform granulation.
No degradation of active ingredients.
The two units can be integrated to:
Transfer wet granules directly from the mixer to the fluid bed.
Reduce manual handling and avoid cross-contamination.
Easily evaluate formulation, processing time, and residual moisture.
Used for:
Development of new pharmaceutical formulations.
Adjustment of excipients, solvents, and granulation parameters.
Process optimization prior to scale-up into large-scale production lines.
Micro-scale R&D Granulation System composed of a 150 g High-Shear Mixer integrated with a 300 g Fluid-Bed Granulator Dryer, manufactured by T&T MACHINERY, is a critical system for pharmaceutical formulation research and process optimization before scaling up to industrial production lines.
Working capacity: approx. 150 g — ideal for formulation studies and new product trials.
Main components:
Main impeller: blends and kneads powder materials.
Chopper blade: breaks wet mass into uniform granules.
Applications:
Wet granulation for tablets or capsules.
Enhances granule uniformity and mechanical strength.
Advantages:
Easy control of mixing speed and processing time.
Suitable for both pharmaceutical and nutraceutical formulations.
Drying capacity: approx. 300 g of wet granules.
Working principle:
Heated air flows upward, fluidizing the granule bed.
Moisture evaporates rapidly, providing uniform drying.
Top-spray granulation system available.
Features:
Adjustable temperature, airflow, and drying time.
Integrated dust filtration system.
Advantages:
Fast drying, uniform granulation,
No degradation of active ingredients.
The two machines are integrated to:
Transfer wet granules directly from the mixer to the fluid bed.
Reduce manual handling and avoid cross-contamination.
Enable accurate evaluation of formulation, processing time, and residual moisture.
Designed for:
New pharmaceutical formulation development.
Adjustment of excipients, solvents, and granulation parameters.
Process optimization prior to scale-up into full-scale production lines.