R&D Hydrolysis Reactor | Lab-Scale Hydrolysis – GMP Compliant | T&T MACHINERY

🔬 R&D Hydrolysis Reactor in the Pharmaceutical Industry

R&D Hydrolysis Reactor in the pharmaceutical field is a specialized device used in research and development to carry out hydrolysis processes—breaking down large molecules (such as proteins, polysaccharides, etc.) into smaller components using water, often combined with heat, acid, alkali, or enzymes.

✅ STRUCTURE OF R&D Hydrolysis Reactor 50L

🔹 Reactor Body

• Material: Stainless steel 316L or heat-resistant glass

• May include a heating jacket or thermal insulation layer

🔹 Reactor Lid

• Sealed with safety locks and heat-resistant gaskets

• Equipped with ports for:
  – Ingredient feeding funnel
  – Temperature and pressure sensors
  – Gauges
  – Safety valves

🔹 Heating System

• Heats via electric heaters or jacketed oil/water circulation

• Controlled by precision temperature sensors

🔹 Stirring System

• Equipped with a motor and internal agitator blades

• Adjustable stirring speed ensures even mixing and prevents clumping

🔹 Sensors & Measuring Instruments

• Includes temperature and pressure gauges

• Automated process control via integrated sensors

🔹 Discharge Valve & Outlet

• Located at the bottom for easy product release after hydrolysis

🔹 Control Panel

• Allows control of temperature, stirring speed, and hydrolysis duration

✅ WORKING PRINCIPLE

1. Feeding Ingredients
Raw materials (such as herbal extracts, pharmaceutical powders, proteins) and water or solvent are loaded into the reactor.

2. Heating
The heating system raises the temperature of the mixture to the desired setpoint (typically 60–120°C, depending on the process).
For enzyme hydrolysis, the temperature is usually lower (40–60°C).

3. Continuous Stirring
The agitator operates continuously to ensure the material is evenly exposed to the solvent and heat.

4. Hydrolysis Reaction
Depending on the method:

• Acid/alkaline hydrolysis: Acid or base is added to the mixture

• Enzymatic hydrolysis: Enzymes are added and the optimal conditions are maintained

5. Monitoring Parameters
Temperature, pressure, and time are automatically controlled via the control panel.

6. Completion & Product Collection
Once the reaction is complete, the hydrolysate is discharged through the outlet valve for further filtration or purification.